High positive predictive value of Xpert in a low rifampicin resistance prevalence setting.
نویسندگان
چکیده
Although drug susceptible tuberculosis (TB) is a curable disease, spread of rifampicin-resistant TB, including multidrug-resistant (MDR)and extensively drug-resistant (XDR)-TB, is a threat to disease control worldwide [1], in particular in Eastern Europe [2]. XpertMTB/RIF (Xpert; Cepheid Inc., Sunnyvale, CA, USA) is an accurate [3] and affordable [4] automated PCR-based assay that detects DNA of Mycobacterium tuberculosis and resistance to rifampicin in ,2 h [5].
منابع مشابه
Performance of Xpert® MTB/RIF among tuberculosis outpatients in Lilongwe, Malawi
BACKGROUND Xpert® MTB/RIF is a molecular test for the detection of Mycobacterium tuberculosis and rifampicin resistance. It is considered to be a great advance over smear microscopy and culture. However, there is very little information regarding the performance characteristics of Xpert MTB/RIF in Malawi. OBJECTIVE We aimed to evaluate the performance of Xpert MTB/RIF in a Malawian setting. ...
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عنوان ژورنال:
- The European respiratory journal
دوره 44 6 شماره
صفحات -
تاریخ انتشار 2014